濾光片集成微流控芯片

這些模塊化微流控芯片設計用于各種類型過濾器和培養(yǎng)基貼片的可逆集成（需單獨訂購）。該裝置由兩個PC（聚碳酸酯）塑料板組成，每個板上有四個用于可逆裝配的集成磁鐵和一個彈性PDMS薄膜，以確保良好的密封性。芯片上部的Luer連接器允許在實驗期間進行液體灌注和動態(tài)流動該組件易于使用，并且可以可逆地訪問芯片中的濾波器和單元，以便進行下游分析。

微流控芯片有三種配置：

a）帶兩個連接器芯片的過濾器集成，用于跨接應用，如死端過濾或跨接灌注。

b）帶有三個連接器芯片的過濾器集成，用于反式或順式貼片應用，如死端過濾、橫流過濾等。

c）帶有四個連接器芯片的過濾器集成，用于反式或順式貼片應用，如死端過濾、橫流過濾或氣液界面細胞培養(yǎng)等。

當過濾器或補片放置在兩個板之間時，四對磁鐵之間的力確保在8千帕的壓力下自動裝配。后，標準的Luer連接器的上板允許一個容易的灌注。

為確保高流量壓力（高達100千帕）下良好的密封性，芯片可放置在手動螺紋夾具中進行組裝和快速操作。在動態(tài)流動條件下的實驗結(jié)束時，可以通過拆開夾鉗和微流控芯片來輕松移除過濾器或補片。可以按照此鏈接訂購夾鉗！

好處

模塊化芯片的可逆補丁集成

用芯片模制的無泄漏Luer接頭

高抗光透明材料

標準顯微鏡玻片尺寸

組裝三個組件以創(chuàng)建完整的微流控平臺：

微流控芯片

夾緊

微濾器

濾光片集成微流控芯片

These modular microfluidic chips were designed for reversible integration of various types of filters and culture patches (to be ordered separately). The setup consists in two plastic plates in PC (Polycarbonate), each having four integrated magnets for reversible assembly and an elastomeric PDMS thin film to ensure good sealing. The Luer Connectors in the upper part of the chip allow liquid perfusion and dynamic flow conditions during your experiments. The assembly is easy to use and with a reversible access to filter and cells in chip for downstream analysis.

The microfluidic chip is available in three configurations:

a) Filter integration with tow connectors chip for trans- patch application, such as dead-end filtration or trans patch perfusion.
b) Filter integration with three connectors chip for trans- or cis- patch application, such as dead-end filtration, cross-flow filtration, etc.
c) Filter integration with four connectors chip for trans- or cis- patch application, such as dead-end filtration, cross-flow filtration, or air/liquid-liquid interface cell culture, etc.

When a filter or patch is placed between the two plates, the force between the four pairs of magnets ensures auto-assembling at pressures up to 8 kPa. Finally, the standard Luer Connectors of the upper plate allow an easy perfusion.

To ensure good sealing with high flow pressures (up to 100 kPa), the chip can be placed in a hand screwed clamp for assembling and fast operation. At the end of your experiment in dynamic flow conditions, the filter or patch can be easily removed by dissembling the clamps and the microfluidic chip. A clamp can be ordered by following this link!

Benefits

• Reversible patch integration thanks to the modular chip
• Leak-free Luer Connection molded with the chip 
• Highly-resistant and optically clear material
• Standard microscope glass slide size

Assemble the three components to create a complete microfluidic platform:

• Microfluidic chip
• Clamp
• Microfilter