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            目錄:北京索萊寶科技有限公司>>抗體>>Polyclonal Antibody>> K101529PAnti-GCR Polyclonal Antibody

            Anti-GCR Polyclonal Antibody
            • Anti-GCR Polyclonal Antibody
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            • SOLARBIO/索萊寶 品牌
            • K101529P 型號
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            • 北京市 所在地
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            屬性

            供貨周期:現(xiàn)貨 規(guī)格:50ul/100ul 貨號:K101529P 應用領域:醫(yī)療衛(wèi)生,環(huán)保,化工,生物產(chǎn)業(yè),農(nóng)林牧漁 主要用途:WB

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            更新時間:2022-08-15 09:22:40瀏覽次數(shù):924評價

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            供貨周期 現(xiàn)貨 規(guī)格 50ul/100ul
            貨號 K101529P 應用領域 醫(yī)療衛(wèi)生,環(huán)保,化工,生物產(chǎn)業(yè),農(nóng)林牧漁
            主要用途 WB
            Anti-GCR Polyclonal Antibody
            應用 WB
            稀釋比例WB 1:3000.
            交叉反應Human

            Anti-GCR Polyclonal Antibody

            英文名稱Anti-GCR Polyclonal Antibody
            宿主Rabbit
            別名GCCR;GCR;GCRST;GR;GRL
            應用WB
            稀釋比例WB 1:3000.
            交叉反應Human
            蛋白分子量86kDa
            Gene ID2908
            保存Store at -20°C. Avoid freeze / thaw cycles.
            儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
            純化方法Affinity purification
            亞型IgG
            免疫原A synthetic peptide of human GCR
            性狀液體
            Public Immunogen Range

            A synthetic peptide of human GCR

            Subcellular LocationsCytoplasm Mitochondrion Nucleus Nucleus
            Swiss ProtP04150
            克隆類型Polyclonal Antibody
            背景資料

            Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A, leading to RNA decay. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth.

             

            Anti-GCR Polyclonal Antibody

             

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