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南京科佰生物科技有限公司
主營產(chǎn)品： atcc代理,ATCC細(xì)胞系,ATCC細(xì)胞株,ATCC細(xì)胞庫購買 |
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聯(lián)系電話
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南京科佰生物科技有限公司
主營產(chǎn)品： atcc代理,ATCC細(xì)胞系,ATCC細(xì)胞株,ATCC細(xì)胞庫購買 |
聯(lián)系電話
| 參考價 | 面議 |
更新時間：2022-07-27 15:36:44瀏覽次數(shù)：710
聯(lián)系我們時請說明是化工儀器網(wǎng)上看到的信息，謝謝!
| 供貨周期 | 現(xiàn)貨 | 規(guī)格 | T-25 Flask |
|---|---|---|---|
| 貨號 | CBP74039 | 應(yīng)用領(lǐng)域 | 生物產(chǎn)業(yè) |
| 主要用途 | 僅限科研使用 |
| CBP74039 | |
| I. Background | |
| CD27 is a member of the tumor necrosis factor (TNF) receptor superfamily, which includes the T cell co-stimulatory receptors OX40, 4-1BB and herpesvirus entry mediator (HVEM). CD27 is expressed on various types of T cells, B cells and a subset of natural killer cells. It activates NF- kB and MAPK/JNK signaling upon interaction with its TNF-like ligand, CD70, which is expressed by numerous tumor cells. Adaptor proteins TRAF2 and TRAF5 can also stimulate CD27 signaling. Activation of CD27 leads to lymphoid proliferation, differentiation, apoptosis, and the induction of long-term memory. The CD27/CD70 pathway is a key target for the development of treatments for cancer and inflammatory diseases. | |
| II. Description | |
HEK293 cell line expressing full length human CD27 (TNFRSF7). | |
| III. Introduction | |
| Host Cell: | HEK293 |
| Expressed gene: | CD-27 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Synonym(s): | CD70 antigen, Tumor Necrosis Factor Ligand Superfamily Member 7, TNFSF7, CD27 Ligand, Ki-24 antigen, CD27-L, CD27LG |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM +10%FBS+1ug/ml puromycin |
| Storage: | Liquid nitrogen |
| Applications: | Binding Assay,FACS |
| IV. Description of Host Cell Line | |
| Organism: | Homo sapiens, human |
| Tissue: | Embryonic kidney |
| Disease: | Normal |
| Morphology: | Epitheloid cell |
| Growth Properties: | Adherent |
| Ⅴ. Representative Data | |
| |
Figure 1. HEK293 cell line expressing full length human CD27 (TNFRSF7). Expression is confirmed by flow cytometry. | |
