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            您現(xiàn)在的位置： 南京科佰生物科技有限公司>>藥靶細(xì)胞株>>GPCR細(xì)胞株>> CBP71057CCR5/Ga15/CHO
            
  
            
    
            
      

      
            
            
            
            
            
            
      
            
      
      
      
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            CBP71057CCR5/Ga15/CHO  
            
      
            
        
            
            
            
               
            
                
            
                  CCR5/Ga15/CHO
                
            
              
            
            
            

            
            
                  
              
                    
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							型號(hào)
							CBP71057
						
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							cobioer/科佰生物
						
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              更新時(shí)間：2022-05-06 10:53:56瀏覽次數(shù)：687
            
					
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            【簡(jiǎn)單介紹】          
            
              
            
                                                    
            
                                    供貨周期
                  現(xiàn)貨
                                                                            規(guī)格
                  T-25 Flask
                                  
            
                                                                      
            
                                    貨號(hào)
                  CBP71057
                                                                            應(yīng)用領(lǐng)域
                  生物產(chǎn)業(yè)
                                  
            
                                                                      
            
                                    主要用途
                  僅限科研使用
                                                
            
        
            
          
            
CCR5/Ga15/CHO 凍存條件：90% FBS+10% DMSO
            
        
            【詳細(xì)說(shuō)明】
                 
            
        
            
          
            CBP71057
            I. Background 
            CCR5 (chemokine (C-C motif) receptor 5) is a receptor for C-C type chemokines MIP-1α, MIP-1? and CCL5. CCR5 plays a role in the control of granulocytic lineage proliferation or differentiation. It also acts as co-receptor with CD4 for primary non-syncytium-inducing strains (macrophage-tropic) of HIV-1 virus.

            II. Introduction
            Host Cell:
            CHO
            Stability:20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
            Gene Synonyms:
            C-C chemokine receptor type 5, CCR5
            Expressed Gene:
            GenBank accession number NM_000579; no expressed tags
            Host Cell:
            CHO-K1
            Stability:
            32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
            Freeze Medium:90% FBS+10% DMSO
            Culture Medium:F-12+10%FBS+3μg/ml puromycin+100μg/ml Hygromycin B
            Mycoplasma Status:Negative
            Storage:Liquid nitrogen immediately upon delivery
            Application(s):
            Functional assay for CCR5 receptor
            Transducer:Gi

            Ⅲ. Description of Host Cell Line
            Organism:Hamster
            Tissue:Ovary
            Morphology: Epithelial
            Growth Properties: Adherent

            Ⅳ. Representative Data
            Concentration-dependent stimulation of intracellular calcium mobilization by MIP-1α in CCR5/Gα15/CHO and Gα15/CHO cells  
            CBP71057.png
            Figure 1. MIP-1α-induced concentration-dependent stimulation of intracellular calcium mobilization in CCR5/Gα15/CHO and Gα15/CHO cells. The cells were loaded with Calcium-4 prior to stimulation with an CCR5 receptor agonist, MIP-1α. The intracellular calcium change was measured by FlexStation.



            
        
            
      
            
      
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