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            當(dāng)前位置：南京科佰生物科技有限公司>>藥靶細(xì)胞株>>GPCR細(xì)胞株>> CBP71349CCR4/β-Arrestin/CHO
            
					
            
				
            
			
            
		
            
		
            
			
            
				
            
					
            CCR4/β-Arrestin/CHO 
            
					
                             
					                    
					    
            
                        
            
                        						    
            
															
            參  考  價(jià):面議  
            
							                            
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            產(chǎn)品型號(hào)CBP71349
            
								
            品牌cobioer/科佰生物
            
	                            
            廠商性質(zhì)代理商
            
	                            								
            所在地南京市
            
							
            
							
                            
            
                                                            
            
							
            
								
            
									更新時(shí)間：2022-05-06 09:58:05瀏覽次數(shù)：846次
								
            
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				                        				                        供貨周期
				                        現(xiàn)貨
				                        				                    				                    				                        規(guī)格
				                        T-25 Flask
				                        				                    
            
				                    				                    				                    				                    
            
				                        				                        貨號(hào)
				                        CBP71349
				                        				                    				                    				                        應(yīng)用領(lǐng)域
				                        生物產(chǎn)業(yè)
				                        				                    
            
				                    				                    				                    				                    
            
				                        				                        主要用途
				                        僅限科研使用
				                        				                    				                
            
				            
            
				            
            
				            CCR4/β-Arrestin/CHOCCR4/β-Arrestin/CHO
            
				        
				        
            
							
            
								
            CBP71349
            I. Background 
            C-C chemokine receptor type 4 is a protein that in humans is encoded by the CCR4 gene.The protein encoded by this gene belongs to the G protein-coupled receptor family. It is a receptor for the following CC chemokines:CCL2 (MCP-1) CCL4 (MIP-1) CCL5 (RANTES) CCL17 (TARC) CCL22 (Macrophage-derived chemokine). Chemokines are a group of small structurally related proteins that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.

            II. Introduction
            Host Cell:
            CHO
            Stability:20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
            Freeze Medium:90% FBS+10% DMSO
            Culture Medium:F12K+10%FBS+5ug/ml puromycin+5ug/ml blasticidin
            Mycoplasma Status:Negative
            Storage:Liquid nitrogen immediately upon delivery
            Application(s):
            Functional assay for CCR4 receptor
            Transducer：N/A

            Ⅲ. Description of Host Cell Line
            Organism:Hamster
            Tissue:Ovary
            Morphology: Epithelial
            Growth Properties: Adherent

            Ⅳ. Representative Data
            Figure 2.Dose response of Human Recombinant CCL22 in CHO-K1 CCR4 β-Arrestin Cell Line (C12).
            Figure 3. Inhibition of CCL22-induced beta-Arrestin Recruitment in CCR4 beta-Arrestin CHO-K1 Cells.


            
							
            
				            
				        
            
                                                                                        
				        
				    
            

				
            
			
            
		
            

               
        

		

		        



  
    
    				
			

		
    
    
    
    
    
    
    
    
    
    

    

     
     
     
	 



	
	
	

            
	
            
		
            
			
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