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            α2-Macroglobulin (human plasma), (purified)

            參   考   價(jià): 1425

            訂  貨  量: ≥1  件

            具體成交價(jià)以合同協(xié)議為準(zhǔn)

            產(chǎn)品型號

            品       牌Enzo Life Sciences

            廠商性質(zhì)代理商

            所  在  地深圳市

            更新時(shí)間:2022-01-28 14:25:30瀏覽次數(shù):739次

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            供貨周期 兩周 規(guī)格 1*1mg
            貨號 BML-SE502-0001 應(yīng)用領(lǐng)域 生物產(chǎn)業(yè)
            主要用途 科研
            α2-Macroglobulin (human plasma), (purified)
            品牌: ENZO產(chǎn)品貨號: BML-SE502-0001規(guī)格: 1*1mg
            如需購買該產(chǎn)品或咨詢其他問題,請聯(lián)系ENZO一級代理商-欣博盛生物

            α2-Macroglobulin (human plasma), (purified)

            Product Details

            MW:725 kDa

            Source:Isolated from human plasma that is tested to be negative for HbsAg, anti-HBc, anti-HCV, and anti-HIV-1 and -2.

            UniProt ID:P01023

            Shipping:Shipped on Blue Ice

            Long Term Storage:-20°C

            Scientific Background:In addition to binding TGF-β and β-amyloid, α2-macroglobulin covalently binds and inhibits a wide range of proteases, including ADAMs, calpains, cathepsins, chymase, clotting factors, kallikreins, MMPs, neutrophil elastase, and proteinase 3.  It also plays a role in the innate immune system, inhibiting parasitic proteases.  When treated with methylamine, it blocks binding of apoE to lipoprotein receptor-related protein (LRP).

            Regulatory Status:RUO - Research Use Only

            Product Literature References

            Cytotoxicity mechanism of α-MMC in normal liver cells through LRP1 mediated endocytosis and JNK activation: L. Wang, et al.; Toxicology 357, 33 (2016), Abstract;


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