国禁国产you女视频网站-亚洲欧美日韩国产精品影院-国产韩国精品一区二区三区久久-欧美日韩一级片在线观看-国产综合永久精品日韩-国产成人一区二区三区-精品人妻少妇嫩草AV无码专区-日韩中文字幕第一页 ,国产精品手机版在线播放_国产性色AV免费观看在线_久久久无码精品亚洲日韩片库网_国产欧美日韩在线视频一区二区_国产—久久香蕉国产线看观看 ,91免费精品国自产拍在线不卡,久久性生大片免费观看性,亚洲成在人线av,男女天天射天天干网站,欧美一区二区三区四区视频,亚洲黄视频在线观看,国产123 ,&

參考價(jià)	￥ 800
訂貨量	≥1盒

抗體

藥物陽性對照抗體

磷酸化抗體

二抗

病毒抗體

標(biāo)簽抗體

內(nèi)參抗體

其它一抗

供貨周期	現(xiàn)貨	應(yīng)用領(lǐng)域	化工,生物產(chǎn)業(yè),能源

Rabbit anti-Twist1 Polyclonal Antibody Acts as a transcriptional regulator. Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 th

詳細(xì)介紹

概述
描述	Rabbit anti-Twist1 Polyclonal Antibody Acts as a transcriptional regulator. Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. This interaction probably involves the basic domains of both proteins. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Regulates cranial suture patterning and fusion. Activates transcription as a heterodimer with E proteins. Regulates gene expression differentially, depending on dimer composition. Homodimers induce expression of FGFR2 and POSTN while heterodimers repress FGFR2 and POSTN expression and induce THBS1 expression. Heterodimerization is also required for osteoblast differentiation.
別名	Twist1抗體;ACS3; B-HLH DNA binding protein; bHLHa38; BPES2; BPES3; Class A basic helix-loop-helix protein 38; CRS; CRS1; CSO; H-twist; OTTHUMP00000116043; SCS; TWIST; Twist basic helix loop helix transcription factor 1; Twist family bHLH transcription factor 1; Twist homolog 1 (Drosophila); Twist homolog 1; TWIST homolog of drosophila; Twist related protein 1; Twist-related protein 1; TWIST1; TWST1_HUMAN;
宿主	Rabbit
特異性	The antibody detects endogenous levels of total Twist1 protein.
反應(yīng)種屬	Human;Mouse;Rat
應(yīng)用	WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
免疫原	A synthesized peptide derived from Human TWIST1(Accession Q15672), corresponding to amino acid residues M1-P24.
性能
濃度	1mg/ml
純化方法	The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin .
類型	Polyclonal Antibody
儲存/保存方法	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
存儲溶液	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
靶標(biāo)
背景說明	Rabbit anti-Twist1 Polyclonal Antibody Acts as a transcriptional regulator. Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. This interaction probably involves the basic domains of both proteins. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Regulates cranial suture patterning and fusion. Activates transcription as a heterodimer with E proteins. Regulates gene expression differentially, depending on dimer composition. Homodimers induce expression of FGFR2 and POSTN while heterodimers repress FGFR2 and POSTN expression and induce THBS1 expression. Heterodimerization is also required for osteoblast differentiation. Represses the activity of the circadian transcriptional activator: NPAS2-ARNTL/BMAL1 heterodimer (By similarity).
組織特異性	Subset of mesodermal cells.
細(xì)胞定位	Nucleus;
UniProt	Q15672
實(shí)驗(yàn)結(jié)果圖
	Western blot analysis of extracts from JK, Raji and HL-60 cells using Twist1 Antibody
溫馨提示：本產(chǎn)品僅作科研實(shí)驗(yàn)使用，不支持臨床等研究