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            武漢艾美捷科技有限公司
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            中英文說明丨艾美捷PD1抗體(BXC-BE0146)

            時間:2023/5/6閱讀:334
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            PD-1/PD-L1 has become a research hotspot in tumor immunotherapy in recent years. Tumor cells recruit immunosuppressive cells and cytokines by overexpressing PD-1/PD-L1, reduce the Antigenicity of tumor cells, and tilt the balance of immune microenvironment from steady state to immunosuppression. This process is called immune editing.

            Immune editing includes three processes: clearing, balancing, and escaping. Tumor cells ultimately evade the anti-tumor effects of the body's immune system through immune editing, forming clinically detectable tumors.

            In recent years, research related to PD-1 antibodies has emerged, which may become a major anti-tumor tool.

             

            Background of PD1 antibody (BXC-BE0146):

            The InVivoMAb anti mouse PD-1 (CD279):

            Research fields: cancer biology, immune checkpoint proteins, immunology;

            Clone number: RMP1-14;

            Antigen: PD-1;

            Host source: rats;

            Antibody subtype: IgG2a, κ;

            Molecular weight: 150 kDa;

            Recommended homotypic control: InVivoMAb anti mouse PD-1 (CD279) product number: BE0089;

            Concentration: usually between 4 and 11 mg/ml depending on the batch;

            Recommended dilution buffer: InVivoPure pH 7.0 dilution buffer, product number: IP0070;

             

            艾美捷 PD1抗體(BXC-BE0146)背景:

            該InVivoMAb 抗小鼠 PD-1 (CD279)(InVivoMAb anti-mouse PD-1 (CD279)):

            研究領(lǐng)域:癌癥生物學(xué), 免疫檢查點蛋白, 免疫學(xué);

            克隆號:RMP1-14;

            抗原:PD-1;

            宿主來源:大鼠;

            抗體亞型:IgG2a, κ;

            分子量:150 kDa;

            推薦同型對照:InVivoMAb 抗小鼠 PD-1 (CD279)貨號為:BE0089;

            濃度:因批次可能不同,通常在4-11 mg/ml之間;

            推薦的稀釋緩沖液:InVivoPure pH 7.0 稀釋緩沖液,貨號:IP0070;

            638189870923105604903.png

            PD1抗體(BXC-BE0146)相關(guān)研究:

            體內(nèi)單克隆抗體抗小鼠PD-1 (CD279) (克隆J43)

            體內(nèi)單克隆抗體抗人類PD-1 (CD279) (克隆J116)

            體內(nèi)單克隆抗體抗人類PD-1 (CD279) (克隆J110)

            體內(nèi)單克隆抗體抗小鼠PD-1 (CD279) (克隆29F.1A12™)

            體內(nèi)加上抗小鼠PD-1(CD279)(克隆J43)

            體內(nèi)加上抗小鼠PD-1(CD279)(克隆29F.1A12™)

            RecombiMAb 抗小鼠 PD-1 (CD279) (D265A) (克隆 RMP1-14-CP151)

            RecombiMAb抗小鼠PD-1 (CD279) (克隆RMP1-14-CP157)

            RecombiMAb抗小鼠PD-1 (CD279) (克隆RMP1-14-CP162)

            體內(nèi)SIM抗人類PD-1(納武利尤單抗生物類似藥)

            體內(nèi)加上抗小鼠PD-1(CD279)(克隆29F.1A12™)

            體內(nèi)SIM抗人PD-1(帕博利珠單抗生物類似藥)(克隆帕博利珠單抗)


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