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            Wnt receptor抗原,Wnt信號(hào)受體蛋白/Frizzled homolog 1抗原

            2024-11-12  閱讀(137)

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            Recombinant human Wnt receptor   

            Frizzled-1; Frizzled homolog 1 (Drosophila); Fz1; hFz1; Fz-1; FZD1; FzE1; Wnt receptor; FZD1_HUMAN.   

            濃度:1mg/ ml

            來源:Recombinant Human

            純度:95% SDS-PAGE

            表達(dá)系統(tǒng):Escherichia coli

            標(biāo)簽:His tag   

            蛋白長度:Full length protein

            內(nèi)毒素水平:<1.000 Eu/µg

            純化方法:HPLC

            應(yīng)用:SDS-PAGE,Western blotELISA

            Biological activity,immunology research

            保存:-20

            保質(zhì)期:1

            Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK3 kinase, nuclear accumulation of beta catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt mediated inactivation of GSK3 kinase. Both pathways seem to involve interactions with G proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Activated by Wnt3A, Wnt3, Wnt1 and to a lesser extent Wnt2, but not by Wnt4, Wnt5A, Wnt5B, Wnt6, Wnt7A or Wnt7B.



            產(chǎn)品名稱:Rabbit Anti-Wnt receptor antibody

            Rabbit Anti-Wnt receptor 

            別名:Frizzled-1; Frizzled homolog 1 (Drosophila); Fz1; hFz1; Fz-1; FZD1; FzE1; Wnt receptor; FZD1_HUMAN.                

            來源:Rabbit

            克隆類型:Polyclonal

            濃度:1mg/ml

            亞型:IgG

            反應(yīng):Human,Rat (predicted: Mouse,Pig,Cow,Chicken,Dog,Horse)

            應(yīng)用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500

                   IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

            免疫原:KLH conjugated synthetic peptide derived from human Wnt receptor

            保存:-20
            保質(zhì)期:1

             

             

            產(chǎn)品名稱:Anti-Wnt receptor antibody

            Mouse Anti-Wnt receptor

            別名:Frizzled-1; Frizzled homolog 1 (Drosophila); Fz1; hFz1; Fz-1; FZD1; FzE1; Wnt receptor; FZD1_HUMAN.                  

            來源:Mouse

            克隆類型:Monoclonal

            濃度:1mg/ml

            亞型:IgG

            反應(yīng):Human

            應(yīng)用:WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500

                   IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

            反應(yīng):  Human

            免疫原:KLH conjugated synthetic peptide derived from human Wnt receptor

            保存:-20
            保質(zhì)期:1

            Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK3 kinase, nuclear accumulation of beta catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt mediated inactivation of GSK3 kinase. Both pathways seem to involve interactions with G proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Activated by Wnt3A, Wnt3, Wnt1 and to a lesser extent Wnt2, but not by Wnt4, Wnt5A, Wnt5B, Wnt6, Wnt7A or Wnt7B.


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