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            VAV1抗原,鳥苷酸轉(zhuǎn)換因子VAV1抗原

            2024-12-4  閱讀(142)

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            Recombinant human VAV1   

            Oncogene vav; p95Vav; Protooncogene vav; Proto-oncogene vav; VAV 1; VAV 1 oncogene; VAV; Vav proto oncogene; Vav proto-oncogene; VAV_HUMAN .  

            濃度:1mg/ ml

            來源:Recombinant Human

            純度:≥95% SDS-PAGE

            表達(dá)系統(tǒng):Escherichia coli

            標(biāo)簽:His tag N-Terminus

            蛋白長度:Full length protein

            內(nèi)毒素水平:<1.000 Eu/µg

            純化方法:HPLC

            應(yīng)用:SDS-PAGE,Western blot,ELISA

            Biological activity,immunology research

            保存:-20℃

            保質(zhì)期:1年

            This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. 



            產(chǎn)品名稱:Rabbit Anti-VAV1  antibody

            Rabbit Anti-VAV1  

            別名:Oncogene vav; p95Vav; Protooncogene vav; Proto-oncogene vav; VAV 1; VAV 1 oncogene; VAV; Vav proto oncogene; Vav proto-oncogene; VAV_HUMAN .     

            來源:Rabbit

            克隆類型:Polyclonal

            濃度:1mg/ml

            亞型:IgG

            應(yīng)用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

            反應(yīng):Human (predicted: Mouse,Rat,Pig,Cow,Horse)

            理論分子量:98kDa

            免疫原:KLH conjugated synthetic peptide derived from human VAV1

            保存:-20
            保質(zhì)期:1

             

            單克隆抗體

            產(chǎn)品名稱:Anti-VAV1 antibody

            Mouse Anti-VAV1 

            別名:Oncogene vav; p95Vav; Protooncogene vav; Proto-oncogene vav; VAV 1; VAV 1 oncogene; VAV; Vav proto oncogene; Vav proto-oncogene; VAV_HUMAN .  

            來源:Mouse

            克隆類型:Monoclonal

            濃度:1mg/ml

            亞型:IgG

            應(yīng)用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

            反應(yīng): Human

            理論分子量:98kDa

            免疫原:KLH conjugated synthetic peptide derived from human VAV1

            保存:-20
            保質(zhì)期:1

            This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. 


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