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上海允麥生物科技有限公司
中級會員·7年
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Recombinant human VASP
Vasodilator stimulated phosphoprotein； Vasodilator-stimulated phosphoprotein； VASP； VASP_HUMAN.
表達(dá)系統(tǒng)：Escherichia coli
應(yīng)用：SDS-PAGE，Western blot，ELISA
Biological activity,immunology research
保質(zhì)期：1年
Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation.
產(chǎn)品名稱：Rabbit Anti-VASP antibody
Rabbit Anti-VASP
別名：Vasodilator stimulated phosphoprotein； Vasodilator-stimulated phosphoprotein； VASP； VASP_HUMAN.
反應(yīng)：Human,Mouse,Rat (predicted: Cow,Dog)
理論分子量：40kDa
免疫原：KLH conjugated synthetic peptide derived from human VASP
保存：-20℃
保質(zhì)期：1年
單克隆抗體
產(chǎn)品名稱：Anti-VASP antibody
別名：Vasodilator stimulated phosphoprotein； Vasodilator-stimulated phosphoprotein； VASP； VASP_HUMAN.
免疫原：KLH conjugated synthetic peptide derived from human VASP
保存：-20℃
保質(zhì)期：1年
Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
