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            Wnt1抗原,信號通路Wnt1抗原

            2024-11-10  閱讀(68)

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            Recombinant human Wnt1   

            wingless-type MMTV integration site family, member 1; INT 1; INT1; Murine mammary tumor virus integration site 1 ; Oncogene INT1; Proto oncogene protein Wnt 1; Wnt 1; Wnt1 proto oncogene protein precursor; WNT1_HUMAN.    

            濃度:1mg/ ml

            來源:Recombinant Human

            純度:95% SDS-PAGE

            表達系統(tǒng):Escherichia coli

            標簽:His tag   

            蛋白長度:Full length protein

            內(nèi)毒素水平:<1.000 Eu/µg

            純化方法:HPLC

            應(yīng)用:SDS-PAGEWestern blot,ELISA

            Biological activity,immunology research

            保存:-20

            保質(zhì)期:1

            TThe WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region.



            產(chǎn)品名稱:Rabbit Anti-Wnt1 antibody

            Rabbit Anti-Wnt1 

            別名:wingless-type MMTV integration site family, member 1; INT 1; INT1; Murine mammary tumor virus integration site 1 ; Oncogene INT1; Proto oncogene protein Wnt 1; Wnt 1; Wnt1 proto oncogene protein precursor; WNT1_HUMAN.               

            來源:Rabbit

            克隆類型:Polyclonal

            濃度:1mg/ml

            亞型:IgG

            反應(yīng):Human,Mouse,Rat (predicted: Cow,Chicken,Horse)

            應(yīng)用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500

                   IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

            理論分子量:39kDa

            免疫原:KLH conjugated synthetic peptide derived from human Wnt1

            保存:-20
            保質(zhì)期:1

             

             

            產(chǎn)品名稱:Anti-Wnt1 antibody

            Mouse Anti-Wnt1

            別名:wingless-type MMTV integration site family, member 1; INT 1; INT1; Murine mammary tumor virus integration site 1 ; Oncogene INT1; Proto oncogene protein Wnt 1; Wnt 1; Wnt1 proto oncogene protein precursor; WNT1_HUMAN.                   

            來源:Mouse

            克隆類型:Monoclonal

            濃度:1mg/ml

            亞型:IgG

            反應(yīng):Human

            應(yīng)用:WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500

                   IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

            反應(yīng):  Human

            理論分子量:39kDa

            免疫原:KLH conjugated synthetic peptide derived from human Wnt1

            保存:-20
            保質(zhì)期:1

            The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region.


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