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上海允麥生物科技有限公司
中級會員·7年
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- 麥經(jīng)理
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Recombinant human Vinexin
SCAM 1; SCAM1; SH3 containing adapter molecule 1; SH3 domain containing adapter molecule 1; SH3D4; Sorbin and SH3 domain containing 3; Sorbin and SH3 domain containing protein 3; Sorbs3; Vinexin alpha; Vinexin; Vinexin beta (SH3 containing adaptor molecule 1).
濃度：1mg/ ml
來源：Recombinant Human
純度：≥95% SDS-PAGE
表達系統(tǒng)：Escherichia coli
標簽：His tag
蛋白長度：Full length protein
內(nèi)毒素水平：<1.000 Eu/µg
純化方法：HPLC
應用：SDS-PAGE，Western blot，ELISA
Biological activity,immunology research
保存：-20℃
保質(zhì)期：1年
Vinexin is a 671 amino acid protein that is expressed as two isoforms, designated Vinexin alpha and Vinexin beta. Localized to cell junctions in both the cytoplasm and the cytoskeleton, Vinexin alpha functions to promote Actin stress fiber formation, playing an important role in modification of the Actin cytoskeleton. Like Vinexin alpha, Vinexin beta is localized to cell junctions in the cytoplasm, but is also found in the nucleus where it plays an important role in cell spreading and in activation of the JNK pathway in response to EGF stimulation. Although Vinexin alpha and Vinexin beta have different roles within the cell, both proteins contain three SH3 domains in their carboxy terminus and are expressed in a variety of tissues, including placenta, heart, liver, brain, pancreas and skeletal muscle. Together, Vinexin alpha and Vinexin beta are involved in cell-cell adhesion, signal transduction and cytoskeletal organization throughout the cell.
產(chǎn)品名稱：Rabbit Anti-Vinexin antibody
Rabbit Anti-Vinexin
別名：SCAM 1; SCAM1; SH3 containing adapter molecule 1; SH3 domain containing adapter molecule 1; SH3D4; Sorbin and SH3 domain containing 3; Sorbin and SH3 domain containing protein 3; Sorbs3; Vinexin alpha; Vinexin; Vinexin beta (SH3 containing adaptor molecule 1).
來源：Rabbit
克隆類型：Polyclonal
濃度：1mg/ml
亞型：IgG
應用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
反應:(predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Dog,Horse)
理論分子量：75kDa
免疫原：KLH conjugated synthetic peptide derived from human Vinexin
保存：-20℃
保質(zhì)期：1年
單克隆抗體
產(chǎn)品名稱：Anti-Vinexin antibody
Mouse Anti-Vinexin
別名：SCAM 1; SCAM1; SH3 containing adapter molecule 1; SH3 domain containing adapter molecule 1; SH3D4; Sorbin and SH3 domain containing 3; Sorbin and SH3 domain containing protein 3; Sorbs3; Vinexin alpha; Vinexin; Vinexin beta (SH3 containing adaptor molecule 1).
來源：Mouse
克隆類型：Monoclonal
濃度：1mg/ml
亞型：IgG
應用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
反應: Human
理論分子量：75kDa
免疫原：KLH conjugated synthetic peptide derived from human Vinexin
保存：-20℃
保質(zhì)期：1年
Vinexin is a 671 amino acid protein that is expressed as two isoforms, designated Vinexin alpha and Vinexin beta. Localized to cell junctions in both the cytoplasm and the cytoskeleton, Vinexin alpha functions to promote Actin stress fiber formation, playing an important role in modification of the Actin cytoskeleton. Like Vinexin alpha, Vinexin beta is localized to cell junctions in the cytoplasm, but is also found in the nucleus where it plays an important role in cell spreading and in activation of the JNK pathway in response to EGF stimulation. Although Vinexin alpha and Vinexin beta have different roles within the cell, both proteins contain three SH3 domains in their carboxy terminus and are expressed in a variety of tissues, including placenta, heart, liver, brain, pancreas and skeletal muscle. Together, Vinexin alpha and Vinexin beta are involved in cell-cell adhesion, signal transduction and cytoskeletal organization throughout the cell.
