1505

TLC中性糖鞘脂混標(biāo) TLC Neutral Glycosphingolipid standard

Glycosphingolipid

1mg/ml

cerebrosides, lactosylceramides, ceramide trihexosides, globosides

-20℃

上?；菡\(chéng)生物提供中性TLC分析生化實(shí)驗(yàn)用糖鞘脂,糖鞘脂(glycosphingolipid,GSL)是由神經(jīng)酰胺和非脂的糖基部分寡糖鏈構(gòu)成,鞘脂包括中性鞘糖脂(糖基不含唾液酸)和酸性鞘糖脂

 Formula Weight:mixture

 Unit:1 mg/ml, 1ml

Solvent:chloroform/methanol, 2:1

Source:natural

Purity:mixture

Analytical Methods:TLC

Natural Source:bovine and porcine

Solubility:chloroform/methanol, 2:1

Physical Appearance:liquid

Storage:-20°C

Composition:cerebrosides, lactosylceramides, ceramide trihexosides, globosides

Application Notes:

    This standard contains four neutral glycosphingolipids for the qualitative identification of unknowns. The mixture is prepared from high purity stock material and contains sphingolipids having one, two, three, and four saccharides. Carbohydrate structures on these glycosphingolipids are synthesized by the sequential addition of monosaccharides by glycosyltransferases. Hence, globoside is derived from ceramide trihexoside which is derived from lactosylceramide which is derived from cerebroside. Glycosphingolipids are involved in many neuronal and degenerative diseases and are therefore being closely investigated in many research areas. This qualitative standard is intended for the use in verifying the identity of unknown samples and is not designed for the quantitative analysis.

參考文獻(xiàn)References: 

1. A. Cremesti and A. Fischl “Current methods for the identification and quantitation of ceramides: An overview” Lipids, Vol. 35:9 pp. 937-945, 2000 

2. J. Bielawski et al. “Comprehensive Quantitative Analysis of Bioactive Sphingolipids by High-Performance Liquid Chromatography–Tandem Mass Spectrometry” Lipidomics, Vol. 579 pp. 443-467, 2010