目錄:MedChemExpress LLC>>信號通路>> WEHI-539 hydrochloride | MedChemExpress
| CAS | 2070018-33-4 | 純度 | 98.31% |
|---|---|---|---|
| 分子量 | 620.18 | 分子式 | C??H??ClN?O?S? |
| 供貨周期 | 現(xiàn)貨 | 規(guī)格 | 10 mM * 1 mL |
| 貨號 | HY-15607A | 應用領域 | 醫(yī)療衛(wèi)生,化工,生物產(chǎn)業(yè),制藥/生物制藥 |
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CAS No. : 2070018-33-4
MCE 國際站：WEHI-539 hydrochloride
產(chǎn)品活性：WEHI-539 hydrochloride 是一種選擇性的 Bcl-XL 抑制劑，IC50 為 1.1 nM。
研究領域：Apoptosis
作用靶點：Bcl-2 Family
In Vitro: WEHI-539 hydrochloride is a selective inhibitor of Bcl-XL. WEHI-539 augments NSC 241240 induced caspase 3/7 activity, PARP cleavage and annexin V labelling. WEHI-539 as a single agent causes noticeable PARP cleavage in Ovcar-4 (5 μM in Ovcar-4.) and Ovsaho (1 μM in Ovsaho) cells.
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