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            BPS Bioscience Inc.
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            當(dāng)前位置:BPS Bioscience Inc.>>Inhibitors / Activators>> 27706-2LDN-57444

            LDN-57444

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            產(chǎn)品型號(hào)27706-2

            品       牌BPS Bioscience

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            更新時(shí)間:2023-12-19 22:38:58瀏覽次數(shù):118次

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            ●Purchase●DescriptionLDN-57444isacellpermeableubiquitinC-terminalhydrolase(UCH-L1)inhibitor(Ki=0
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            Description

            LDN-57444 is a cell permeable ubiquitin C-terminal hydrolase (UCH-L1) inhibitor (Ki=0.4 μM). Decreases proteasome activity and increases levels of ubiquitinated proteins. Induces apoptosis and causes dramatic alterations in synaptic protein distribution and spine morphology in vivo. LDN-57444 is a useful tool to study UCH-L1 in different pathological conditions such as cancer and neurodegeneration.

            Synonyms
            1H–Indole–2,3–dione, 5–chloro–1–[(2,5–dichlorophenyl)methyl]–, 3–(O–acetyloxime)

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