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參考價(jià)	￥ 1118
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￥1118

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供貨周期	現(xiàn)貨	規(guī)格	10mg;50mg
貨號(hào)	abs42236361	主要用途	A selective leukocyte elastase inhibitor

Sivelestat sodium salt is a selective leukocyte elastase inhibitor (IC50 = 44 nM).

產(chǎn)品描述
描述	Sivelestat sodium salt is a selective leukocyte elastase inhibitor (IC50 = 44 nM). Through in vitro observations, Sivelestat functions by blocking LTB4-induced neutrophil transmigration and NF-κB activation.
應(yīng)用	A selective leukocyte elastase inhibitor
純度	≥98%
儲(chǔ)存/保存方法	Desiccate at room temperature
形態(tài)	Solid
基本信息
別名	N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt
IC50	Leukocyte elastase: IC50 = 44 nM; neutrophil elastase: IC50 = 44 nM (human); Leukocyte elastase: IC50 = 19-49 nM (rabbit, rat, hamster and mouse)
Ki 數(shù)據(jù)	neutrophil elastase: Ki= 0.2 nM (human)
可溶性/溶解性	Soluble in DMSO (50 mM).
MDL	MFCD08461731
PubChem CID	23664980