MHA 髓樣/組織細(xì)胞抗原

廣州健侖生物科技有限公司

MAC387 識別白細(xì)胞抗原L1，屬于S-100 蛋白家族成員，表達(dá)于粒細(xì)胞、單核細(xì)胞、巨噬細(xì)胞、粘膜鱗狀上皮細(xì)胞及反應(yīng)性上皮細(xì)胞?？捎糜谘芯苛＜?xì)胞、單核細(xì)胞、巨噬細(xì)胞及大部分的組織細(xì)胞。MAC387多作為巨噬細(xì)胞的參考依據(jù)，敏感度較高，但不如CD68 特異。

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MHA 髓樣/組織細(xì)胞抗原

【產(chǎn)品介紹】

細(xì)胞定位：細(xì)胞漿/細(xì)胞核

克隆號:NAC387

同型：IgG

適用組織：石蠟/冰凍

陽性對照：扁桃體

抗原修復(fù)：熱修復(fù)（EDTA）

抗體孵育時間：30-60min

MHA

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【公司名稱】 廣州健侖生物科技有限公司
【市場部】     歐

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【騰訊  】 
【公司地址】 廣州清華科技園創(chuàng)新基地番禺石樓鎮(zhèn)創(chuàng)啟路63號二期2幢101-103室

爾加里大學(xué)干細(xì)胞生物學(xué)助理教授杰夫·比爾內(nèi)斯克表示，抗原抗體底部擁有特定的細(xì)胞組織——真皮抗原抗體，其負(fù)責(zé)給表皮細(xì)胞發(fā)送信號以重建抗原抗體，產(chǎn)生新發(fā)。抗原抗體具有一定的再生和衰退周期。
比爾內(nèi)斯克解釋說，脫發(fā)特別是男性禿頂?shù)闹饕蚴强乖贵w中的真皮抗原抗體產(chǎn)生了功能障礙。對禿頂皮膚進(jìn)行觀察可以發(fā)現(xiàn)，要么是真皮抗原抗體細(xì)胞的大量缺失，要么是這些細(xì)胞已經(jīng)抗原抗體。
研究發(fā)現(xiàn)，位于真皮鞘內(nèi)的鄰近細(xì)胞對那些可為真皮抗原抗體重新注入新細(xì)胞的干細(xì)胞具有庇護(hù)作用，從而維持人體長出新發(fā)的能力。通過對真皮鞘內(nèi)的細(xì)胞進(jìn)行標(biāo)記，研究人員發(fā)現(xiàn)小量真皮鞘細(xì)胞能自我更新，并為每個抗原抗體帶來數(shù)以百計的新細(xì)胞。此項新發(fā)現(xiàn)使研究人員進(jìn)一步了解了抗原抗體的再生機(jī)理，為開發(fā)出以干細(xì)胞為靶標(biāo)的頭發(fā)再生治療方法打開了大門。

Jeff Biernesk, an assistant professor of stem cell biology at the University of Calgary, says that the bottom of the antigen-antibody has a specific cell-tissue antigen called dermal antigen, which is responsible for sending signals to the epidermal cells to rebuild the antigen and produce new hair. Antigen antibodies have a certain period of regeneration and recession.
Billnec explained that the main reason for alopecia, especially in male baldness, is the dysfunction of dermal antigen antibodies in antigenic antibodies. Observation of bald skin can be found either as a substantial loss of dermal antigen antibody cells or because these cells are already antigen-antibodies.
The study found that adjacent dermal sheath cells to those who can dermal antigen antibody re-injection of new cells with the protection of stem cells in order to maintain the ability of the body to grow new hair. By labeling cells in the dermal sheath, researchers found that a small number of dermal sheath cells self-renew and bring hundreds of new cells per antigen-antibody. This new discovery gives researchers further insight into the mechanism of antigen-antibody regeneration, opening the door to developing hair-regeneration treatments that target stem cells.