詳細(xì)介紹
MLH1抗體 錯(cuò)配修復(fù)蛋白1抗體
廣州健侖生物科技有限公司
MLH1(MutL protein homolog 1)是一種錯(cuò)配修復(fù)蛋白,其基因定位在3號(hào)染色體P臂的21.3位上。突變型的錯(cuò)配修復(fù)蛋白常表達(dá)于高頻度微衛(wèi)星不穩(wěn)定(MSI-H)患者中,與常染色體的顯性遺傳相關(guān),也稱為遺傳性非息肉病性結(jié)、直腸癌(HNPCC),也可見于散發(fā)性(MSI-H)結(jié)、直腸癌患者。MLH1、MSH2、MSH6抗體可用于患者及其家族對(duì)該疾病的篩查研究。文獻(xiàn)報(bào)道高頻度微衛(wèi)星不穩(wěn)定(MSI-H)的結(jié)、直腸癌患者比低頻度微衛(wèi)星不穩(wěn)定性(MSI-L)及微衛(wèi)星穩(wěn)定(MSS)的患者的預(yù)后好。
我司還提供其它進(jìn)口或國產(chǎn)試劑盒:登革熱、瘧疾、流感、A鏈球菌、合胞病毒、腮病毒、乙腦、寨卡、黃熱病、基孔肯雅熱、克錐蟲病、違禁品濫用、肺炎球菌、軍團(tuán)菌、化妝品檢測(cè)、食品安全檢測(cè)等試劑盒以及日本生研細(xì)菌分型診斷血清、德國SiFin診斷血清、丹麥SSI診斷血清等產(chǎn)品。
歡迎咨詢
歡迎咨詢
MLH1抗體 錯(cuò)配修復(fù)蛋白1抗體
【產(chǎn)品介紹】
細(xì)胞定位:細(xì)胞漿/細(xì)胞核
克隆號(hào):ES05
同型:IgG
適用組織:石蠟/冰凍
陽性對(duì)照:直腸癌
抗原修復(fù):熱修復(fù)(EDTA)
抗體孵育時(shí)間:60min
產(chǎn)品編號(hào) | 抗體名稱 | 克隆型別 |
OB160 | Melanoma Associated Antigen(黑色素瘤相關(guān)抗原) | KBA.62 |
OB161 | Melanoma(黑色素瘤) | HMB-45 |
OB162 | Mesothelial Cell 間皮細(xì)胞 | HBME-1 |
OB163 | MGMT(甲基鳥嘌呤甲基轉(zhuǎn)移酶) | UMAB56 |
OB164 | MHA (髓樣/組織細(xì)胞抗原) | MAC387 |
OB165 | MLH1(錯(cuò)配修復(fù)蛋白1) | ES05 |
OB166 | MPO(髓過氧化物酶) | polyclonal |
OB167 | MSH2(錯(cuò)配修復(fù)蛋白2) | G219-1129 |
OB168 | MSH6(錯(cuò)配修復(fù)蛋白6) | SP93 |
OB169 | MUC1(粘蛋白1) | MRQ-17 |
OB170 | MUC2(粘蛋白2) | MRQ-18 |
OB171 | MUC5AC(粘蛋白5AC) | MRQ-19 |
OB172 | MUM1(多發(fā)性骨髓瘤致癌蛋白) | MRQ-8 |
OB173 | MyoD1(橫紋肌肉瘤標(biāo)志) | EP212 |
OB174 | Myogenin(肌漿蛋白) | F5D |
OB175 | Myoglobin(肌紅蛋白) | polyclonal |
OB176 | Myoglobin(肌紅蛋白) | MGN01 |
OB177 | Myosin Heavy Chain (Smooth Muscle)肌球蛋白重鏈(平滑?。?SMMHC | SMMS-1 |
OB178 | Napsin A(天冬氨酸蛋白酶4) | MRQ-60 |
OB179 | N-Cadherin (鈣粘附蛋白-N) | 6G11 |
OB180 | Nestin (巢蛋白) | 10C2 |
MLH1抗體
想了解更多的產(chǎn)品及服務(wù)請(qǐng)掃描下方二維碼:
【公司名稱】 廣州健侖生物科技有限公司
【市場(chǎng)部】 歐
【】
【騰訊 】
【公司地址】 廣州清華科技園創(chuàng)新基地番禺石樓鎮(zhèn)創(chuàng)啟路63號(hào)二期2幢101-103室
MLH1 (MutL protein homolog 1) is a mismatch repair protein whose gene is located on chromosome 21.3 of P-arm of chromosome 3. Mutant mismatch repair proteins are often expressed in high frequency microsalite instability (MSI-H) patients and are associated with autosomal dominant inheritance, also known as hereditary nonpolyposis colorectal (HNPCC) , Can also be found in sporadic (MSI-H) node, rectal cancer patients. MLH1, MSH2, MSH6 antibodies are useful in screening studies of this disease in patients and their families. It has been reported in the literature that high frequency microsalite instability (MSI-H) nodes and rectal cancer patients have a better prognosis than low frequency microsalite instability (MSI-L) and microsalite stable (MSS) patients.